溶解性 | Soluble in 100% ethanol, ether, oils, 70% alcohol, glacial acetic acid, chloroform, and aqueous sodium hydroxide. Insoluble in water. |
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敏感性 | 对空气和光线敏感 |
存贮条件 | 储存温度2-8℃,充氩保存 |
折光率 | 1.54-1.542 |
沸点 | 255°C |
熔点 | -12--10°C |
密度 | 1.0700 |
荧光 | 否 |
IC50 | 否 |
pK Values | 否 |
别名 | 丁子香酚;丁香油酚;丁子香酸;4-烯丙基-2-甲氧基苯酚; 4-烯丙基愈创木酚;2-Methoxy-4-(2-propenyl)phenol;4-Allyl-2-methoxyphenol;4-Allylguaiacol |
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产品介绍 | 具有强烈的丁香气和辛香气,在空气中色渐变深且稠。能与乙醇、乙醚、氯仿和油类混溶,溶于冰乙酸和苛性碱溶液,几乎不溶于水。低毒,半数致死量(大鼠,经口)2680mg/kg。有刺激性 |
用途 | An antifungal antimicrobial agonist of the TRPV1 receptor. |
生化机理 | Eugenol is a small molecule with structural analogy to Capsaicin that demonstrates agonism of the TRPV1 receptor. Eugenol is described to activate inward currents at the TRPV1, and this action is antagonized by the Capsaicin antagonist Capsazepine. Agonism of the TRPV1 by Eugenol has been correlated with an anesthetic effect. Eugenol also demonstrates antifungal and antimicrobial activity, showing efficacy against Candida albicans biofilms, Listeria monocytogenes and Escherichia coli. Eugenol is further described to induce reactive oxygen species (ROS) production and to scavenge ROS, thus demonstrating prooxidant and antioxidant effects. |
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