属性
溶解性 Soluble in DMSO (75 mM), and ethanol (5 mM).
存贮条件 储存温度2-8°C
描述
产品介绍 iCRT-14是β-catenin应答转录（CRT）抑制剂，在wnt通路实验中IC50为40.3 nM
别名 iCRT14;iCRT 14;iCRT14;iCRT 14; 5-[[2,5-Dimethyl-1-(3-pyridinyl)-1H-pyrrol-3-yl]methylene]-3-phenyl-2,4-thiazolidinedione
生化机理 iCRT 14 is a potent inhibitor of β-catenin-responsive transcription (CRT) (IC50 = 40.3 nM in assays of Wnt pathway activity). iCRT 14 may also directly influence the interaction between β-catenin and TCF4.
应用 A potent beta-catenin inhibito