属性
溶解性 Soluble in DMSO (25 mg/ml), ethanol (100 mM), and methanol.
描述
别名 马来酸伊索拉定;马来酸依索拉啶;2,4-二氨基-6-(2,5-二氯苯基)-1,3,5-三嗪顺丁烯二酸盐;2,4-Diamino-6-(2,5-dichlorophenyl)-1,3,5-triazine Maleate;6-(2,5-Dichlorophenyl)-1,3,5-triazine-2,4-diamine (2Z)-2-butenedioate
生化机理 It is an inhibitor of phosphodiesterase 4 (PDE4) with gastroprotective activity. Irsogladine maleate is a mucosal protective drug with a number of activites including facilitation of gap junctional intercellular communication, inhibition of the reduced gastric mucosal blood flow response, and suppression of reactive oxygen species (ROS) production.
应用 A PDE4 inhibitor and muscarinic acetylcholine receptor binder.