属性
折光率 1.54
密度 1.6000
熔点 178.44° C
溶解性 Soluble in ethanol (26.6 mg/ml), DMSO (5.3 mg/ml), 45% (w/v) aq 2-hydroxypropyl-β-cyclodextrin (0.47 mg/ml), and 0.1 M NaOH (5.2 mg/ml). Insoluble in water
描述
产品介绍 NS-1619是 Ca2+-activated K+-channel选择性激动剂。
别名 ;1-(2-hydroxy-5-(trifluoromethyl)phenyl)-5-(trifluoromethyl)-1H-benzo[d]imidazol-2(3H)-one
生化机理 NS-1619 is a selective MaxiKα (large conductance calcium activated potassium channel) activator. In neutrophils, NS-1619 activation of BKCa channels increased alkalinization of phagocytic vacuoles.
应用 A selective large conductance calcium activated potassium channel activator