属性
溶解性 Slightly soluble in water.
描述
产品介绍 Enalaprilat is the active form of Enalapril. Enalapril is a ACE (angiotensin-converting enzyme) inhibitor, suggested to be more potent than Captopril. Studies indicate that Enalapril downregulates the expression of IL-β, IL-6, and NF-κB. Further studies show that Enalapril upregulates the expression of VEGF and heme oxygenase-1. Enalaprilat reports demonstrate that the compound has some antioxidant activity, which does not include the PKC-NADPH oxidase pathway.
别名 N-[(S)-1-羧基-3-苯丙基]-L-丙氨酰-L-脯氨酸;依那普利拉;(2S)-1-[(2S)-2-[[(1S)-1-Carboxy-3-phenyl-propyl]amino]propanoyl]pyrrolidine-2-carboxylic acid; N-[(1S)-1-Carboxy-3-phenylpropyl]-L-alanyl-L-proline; Enalaprilic acid; Enalaprilatum
应用 An active metabolite of Enalapril.