GA111753 10326-27-9
Barium chloride dihydrate
属性
敏感性 对湿度敏感
折光率 1.635
密度 3.8600
熔点 963°C
溶解性 易溶于水,溶于甲醇,不溶于乙醇、乙酸乙酯和丙酮。
存贮条件 密封保存。
描述
产品介绍 味苦咸。微有吸湿性。在100℃时即失去结晶水,但放置在湿空气中又重新吸收二分子结晶水。中等毒,半数致死量(大鼠,经口)118mg/kg(以无水物计)。
别名 二水合氯化钡; 氯化钡二水合物 ;
生化机理 Barium chloride produces excitatory effects on neuronal signaling through mobilization of intracellular Ca2+. This has been correlated to causing increases in potential difference and short-circuit currents in stripped sheets of rat intestine with subsequent effects on intestinal secretion. The toxic effects of Ba2+ are mediated through neuronal excitation, and sub-toxic administration of Barium Chloride produces arrhythmias in animals. Barium Chloride-promoted arrhythmias have been employed in studies investigating antiarrhythmic compounds. Barium Chloride demonstrates selective inhibition of MMP-2 (matrix metalloproteinase 2), suggested to proceed through displacement by Ba2+ of a Ca2+ ion at the catalytic center of MMP-2.
应用 测定硫酸盐和硒酸盐等,色谱分析,点滴分析测定铂,软水剂。织物染色。
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