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  1. 试剂
  2. 氨基酸类
  • N-乙酰-L-半胱氨酸 ,99%

  • E04006 616-91-1

    N-Acetyl-L-Cysteine

产品订购
产品货号重量货期 优惠价 数量
E04006-100g 100g 准现货 询价
E04006-25g 25g 准现货 询价
E04006-500g 500g 准现货 询价
E04006-1kg 1kg 准现货 询价
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  • 产品信息

属性

溶解性 Soluble in water (100 mg/ml) with heating and obtained a clear, colorless solution, 1 in 2 of ethanol, DMSO (≥33 mg/ml) at 25 °C, hot isopropyl alcohol, methyl acetate, ethyl acetate and methanol. Practically insoluble in chloroform, and ether.
存贮条件 储存温度2-8℃
熔点 109-111°C
密度 否
旋光率 24 ° (JPC Method)
荧光 否
IC50 否
pK Values 否

描述

别名 乙酰半胱氨酸;N-乙酰半胱氨酸;D-3-(2-萘基)-丙氨酸;LNAC;NAC;Ac-Cys-OH;LNAC; N-Acetyl-3-mercaptoalanine; NAC
产品介绍 N-Acetyl-L-cysteine is an acetylated amino acid with antioxidant and mucolytic properties. These two activities have made N-Acetyl-L-cysteine particularly relevant in cystic fibrosis studies, where the antioxidant/reducing character of the compound is described to ameliorate the characteristic systemic redox imbalance state of cystic fibrosis and the mucolytic properties of the compound are shown to impede upon the congestion and inflammation correlated to this redox state. As a mucolytic, N-Acetyl-L-cysteine serves to dissipate disulfide bonds across mucoproteins, loosening and clearing the viscosity of sputum. N-Acetyl-L-cysteine shows complimentary action to glutathione, both demonstrating antioxidant activity through their thiol functionality, and both are shown to protect against peroxidative stress related to septic shock. N-Acetyl-L-cysteine has also been shown to induce apoptosis in vascular smooth muscle cells, indicating that these cells respond differently to changes in reduction-oxidation state than other tissues that are normally protected by the presence of antioxidants. This observation in vascular smooth muscle cells indicates N-Acetyl-L-cysteine as an interventional tool upon arteriosclerotic proliferation of these cells.
用途 An antioxidant mucolytic acetylated amino acid.

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