属性
敏感性 对热敏感
溶解性 Soluble in water (4 mg/ml), and 50% ethanol (150 mg/ml).
存贮条件 储存温度-20°C，充氩储存
描述
产品介绍 Carmustine is a cell-cycle phase nonspecific alkylating antineoplastic agent
别名 卡莫司汀;卡氮芥;双氯乙亚硝脲;1,3-双(2-氯乙基)-1-亚硝基脲;1,3-Bis(2-chloroethyl)-1-nitrosourea ;Nitrumon; Carmubris; Gliadel;BCNU
生化机理 Carmustine is a member of the antineoplastic nitrosourea compounds. Carmustine can perform both alkylating and carabamoylating action and owes part of its cytotoxicity to its demonstrated ability to produce interstrand DNA cross linking. In addition, this compound has been documented as an inhibitor of glutathione reductase, trypanothione reductase, and lipoamide dehydrogenase (DLD).
应用 A DNA alkylating and cross-linking agent used in the treatment of brain tumors and various other malignant neoplasmsv