溶解性 | Soluble in EtOH, acetone (50 mg/ml), DMSO (300 mg/ml), ethanol, and methanol. Insoluble in water |
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存贮条件 | 储存温度 2-8°C |
熔点 | 84-100°C |
密度 | 否 |
荧光 | 否 |
IC50 | 否 |
pK Values | 否 |
别名 | Oligomycin |
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产品介绍 | Oligomycin is a macrolide that acts as a specific inhibitor of the mitochondrial ATP-synthase and blocks oxidative phosphorylation. The compound is a mixture of isomers A ,B , and C .Cancer cell studies show that Oligomycin does not activate the hypoxia-induced factor, however, it enhances the bioenergetic adaptation of heterogeneous bioenergetically organized cells. Oligomycin has been shown to decreased the cyclin D1 protein expression levels |
用途 | A specific inhibitor of the mitochondrial ATP-synthase. |
生化机理 | Macrolide antibiotic; inhibits mitochondrial ATPase and phosphoryl group transfer. |
备注 | 该产品为A, B 和 C的混合物 |
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