• Trimethoprim ,≥99%
  • G63574 738-70-5

    Trimethoprim

产品订购
产品货号重量货期 优惠价 数量
G63574-5g 5g 准现货 询价
G63574-25g 25g 准现货 询价
G63574-100g 100g 准现货 询价
  • 产品信息

属性

溶解性 Soluble in water (0.4 mg/ml), ethanol (2.6 mg/ml at 20 °C), methanol (12.1 mg/ml), chloroform (22.2 mg/ml at 20 °C), and DMSO (50 mg/ml).
敏感性 对光线和湿度敏感
存贮条件 储存温度 2-8°C ,充氩储存
熔点 199-203℃
密度
荧光
IC50
pK Values

描述

别名 甲氧苄啶;2,4-二氨基-5-(3,4,5-三甲氧基苄基)嘧啶;甲氧苄氨嘧啶;5-[(3,4,5-三甲氧基苯基)-甲基]-2,4-嘧啶二胺;2,4-Diamino-5-(3,4,5-trimethoxybenzyl)pyrimidine;Trimpex; Proloprim
产品介绍 Trimethoprim 是一种抑制细菌的抗生素,主要用于预防和尿路感染
用途 An antibacterial agent which selectively inhibits dihydrofolate reductase.
生化机理 Trimethoprim is an antibacterial agent which selectively inhibits DHFR(dihydrofolate reductase) in prokaryotic microorganisms. in addition, trimethoprim is often combined with sulfamethoxazole to inhibit the growth of Staphylococcus aureus. Studies suggest that electro-oxidation of trimethoprim is pH dependent and irreversible. Alternate studies show that trimethoprim can synergize with oxygen causing an increase in oxygen tensions in vitro, which decreases the minimal inhibitory concentrations of trimethoprim resulting in bactericidal effects.

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