相关栏目：
  1. 生物科学
  • Clotrimazole ,≥98.0%(HPLC)

  • G63587 23593-75-1

    Clotrimazole

产品订购
产品货号重量货期 优惠价 数量
G63587-5g 5g 准现货 询价
G63587-25g 25g 准现货 询价
G63587-100g 100g 准现货 询价
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  • 产品信息

属性

溶解性 Soluble in DMSO (25 mM), chloroform (50 mg/ml), DMF, ethyl acetate, ethanol, methanol, and acetone.
熔点 141-149° C
密度 否
荧光 否
IC50 否
pK Values 否

描述

别名 1-[(2-氯苯基)二苯甲基]-1H-咪唑;三苯氯甲咪唑;氯苯甲咪唑;克霉唑;1-[(2-氯苯基)二苯甲基]咪唑;1-(2-氯三苯甲基)咪唑;1-[(2-Chlorophenyl)diphenylmethyl]-1H-imidazole;1-(o-Chlorotrityl)imidazole ;1-[(2-Chlorophenyl)diphenylmethyl]imidazole ;1-(2-Chlorotrityl)imidazole
产品介绍 Clotrimazole是一种合成的抗真菌药物，是imidazole的广谱衍生物
用途 An antifungal compound and CYP inhibitor
生化机理 Clotrimazole is an imidazole derivative and an antifungal compound and a CYP (cytochrome P450) inhibitor. Clotrimazole has been shown to block the intermediate-conductance, IK1 channels (Ca2+ activated K+ channels), in cells such as erythrocytes. In vitro studies of various yeast strains have demonstrated susceptibility to clotrimazole. Clotrimazole is an activator of MB67 and an inhibitor of CYP3A4 and CYP51A1.
备注 Clotrimazole is a synthetic, antifungal and broad-spectrum derivate of imidazole.

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