壬二酸 99%_123-99-9_Azelaic acid 99%

产品货号	规格	货期	优惠价
G64417_1	100g	准现货	询价
G64417_2	2.5kg	准现货	询价
G64417_3	25g	准现货	询价
G64417_4	500g	准现货	询价

产品货号

规格

货期

优惠价

数量

G64417_1

100g

准现货

询价

G64417_2

2.5kg

准现货

询价

G64417_3

25g

准现货

询价

G64417_4

500g

准现货

询价

溶解性	Soluble in water (2.4 mg/ml at 20 °C), ethanol (5%), DMSO, methanol (70 mg/ml), and alcohol.
敏感性	对湿度敏感
存贮条件	密封保存。
折光率	1.4303
沸点	286°C
熔点	109-111°C
密度	0.8210
荧光	否
IC50	否
pK Values	否

溶解性

Soluble in water (2.4 mg/ml at 20 °C), ethanol (5%), DMSO, methanol (70 mg/ml), and alcohol.

敏感性

对湿度敏感

存贮条件

密封保存。

折光率

1.4303

沸点

286°C

熔点

109-111°C

密度

0.8210

荧光

否

IC50

否

pK Values

否

别名	杜鹃花酸;1,7-壬二酸;庚烷-1,7-二羟酸;王二酸;1,7-庚二甲酸;;Nonanedioic acid;1,7-heptanedicarboxylic acid;
产品介绍	Azelaic acid is a dicarboxylic acid that exhibits anti-inflammatory activity. It is known for it’s anti acne activity in vitro. Azelaic acid directly inhibits kallikrein 5 (KLK5), downregulating expression of KLK5, toll-like receptor 2 (TLR 2), and cathelicidin, and suppresses activity of serine proteases in vitro, in vivo, and in clinical settings. In PUFA-treated fibroblasts, azelaic acid decreases generation of ROS and upregulates expression of antioxidative enzymes, inhibiting cell damage; agonist activity at PPARν is thought to drive these effects. Azelaic acid also inhibits proliferation of melanocytes. This compound displays antiacne and anticancer potential as well, inhibiting the proliferation of cutaneous melanoma due to suppression of mitochondrial oxidoreductive activity and DNA synthesis.
用途	An antiinflammatory compound

别名

杜鹃花酸;1,7-壬二酸;庚烷-1,7-二羟酸;王二酸;1,7-庚二甲酸;;Nonanedioic acid;1,7-heptanedicarboxylic acid;

产品介绍

Azelaic acid is a dicarboxylic acid that exhibits anti-inflammatory activity. It is known for it’s anti acne activity in vitro. Azelaic acid directly inhibits kallikrein 5 (KLK5), downregulating expression of KLK5, toll-like receptor 2 (TLR 2), and cathelicidin, and suppresses activity of serine proteases in vitro, in vivo, and in clinical settings. In PUFA-treated fibroblasts, azelaic acid decreases generation of ROS and upregulates expression of antioxidative enzymes, inhibiting cell damage; agonist activity at PPARν is thought to drive these effects. Azelaic acid also inhibits proliferation of melanocytes. This compound displays antiacne and anticancer potential as well, inhibiting the proliferation of cutaneous melanoma due to suppression of mitochondrial oxidoreductive activity and DNA synthesis.

用途

An antiinflammatory compound

个人防护设备	Eyeshields,Gloves,type N95 (US),type P1 (EN143) respirator filter
安全声明（欧洲）	S24/25
RIDADR	否
WGK德国	1
闪点（华氏）	N/A
闪点（摄氏）	210 °C
RTECS	CM1980000
是否危化品	否

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属性

描述

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