黄芩素,98%使用说明书与操作注意事项

产品货号	重量	货期	优惠价
W52004-1g	1g	准现货	询价
W52004-5g	5g	准现货	询价
W52004-25g	25g	准现货	询价

产品货号

重量

货期

优惠价

数量

W52004-1g

准现货

询价

W52004-5g

准现货

询价

W52004-25g

25g

准现货

询价

溶解性	Soluble in alcohol, methanol, ether, acetone, ethyl acetate, hot glacial acetic acid, dilute sodium hydroxide, and DMSO (50 mM). Insoluble in water
敏感性	对光和热敏感
存贮条件	储存温度2-8℃
熔点	256-271°C
密度	1.5480
荧光	否
IC50	否
pK Values	否

溶解性

Soluble in alcohol, methanol, ether, acetone, ethyl acetate, hot glacial acetic acid, dilute sodium hydroxide, and DMSO (50 mM). Insoluble in water

敏感性

对光和热敏感

存贮条件

储存温度2-8℃

熔点

256-271°C

密度

1.5480

荧光

否

IC50

否

pK Values

否

别名	三羟黄酮; 黄芩苷元; 黄芩黄素; 黄芩甙元; 5,6,7-三羟基黄酮;5,6,7-Trihydroxyflavone
产品介绍	Baicalein is a cell-permeable flavone, originally isolated from the roots of Scutellaria baicalensis, that inhibits cellular Ca2+ uptake, calcium mobilization, and adjuvant-induced arthritis. Baicalein has been shown to inhibit platelet 5-LO (5-lipoxygenase) (IC50=9.5 mM) and 12-LO (12-lipoxygenases) (IC50=0.12 mM) and reverse transcriptase. Baicalein reduces leukotriene biosynthesis and inhibits the release of lysosomal enzymes. Baicalein is a potent anti-inflammatory and anti-tumor agent, and it blocks PREP (prolyl oligopeptidase). Baicalein induces the S-phase arrest and apoptosis in proliferation of human lung squamous carcinoma CH27 cells. The declining expression of cdk1, cdk2, cyclin D2 and cyclin A by Baicalein resulted in the G1 and G2 cell cycle arrest in C6 rat glioma cells. Baicalein has anti-thrombotic, antiproliferative and anti-mitogenic effects. Baicalein inhibits protein tyrosine kinase in leukemia (CEM) cells and PMA-stimulated PKC (protein kinase C). Baicalein is an inhibitor of 15-LO and CYP2C9.
用途	An inhibitor of Ca2+ uptake, 5-LO, and 12-LO
生化机理	中药类黄酮的组成成分，黄芩的主要黄酮，抑制花生四烯酸代谢中的12-脂肪氧化酶路径（12-lipoxygenase ，12-LOX），此路径能抑制癌细胞的增殖，诱导凋亡途径。

别名

三羟黄酮; 黄芩苷元; 黄芩黄素; 黄芩甙元; 5,6,7-三羟基黄酮;5,6,7-Trihydroxyflavone

产品介绍

Baicalein is a cell-permeable flavone, originally isolated from the roots of Scutellaria baicalensis, that inhibits cellular Ca2+ uptake, calcium mobilization, and adjuvant-induced arthritis. Baicalein has been shown to inhibit platelet 5-LO (5-lipoxygenase) (IC50=9.5 mM) and 12-LO (12-lipoxygenases) (IC50=0.12 mM) and reverse transcriptase. Baicalein reduces leukotriene biosynthesis and inhibits the release of lysosomal enzymes. Baicalein is a potent anti-inflammatory and anti-tumor agent, and it blocks PREP (prolyl oligopeptidase). Baicalein induces the S-phase arrest and apoptosis in proliferation of human lung squamous carcinoma CH27 cells. The declining expression of cdk1, cdk2, cyclin D2 and cyclin A by Baicalein resulted in the G1 and G2 cell cycle arrest in C6 rat glioma cells. Baicalein has anti-thrombotic, antiproliferative and anti-mitogenic effects. Baicalein inhibits protein tyrosine kinase in leukemia (CEM) cells and PMA-stimulated PKC (protein kinase C). Baicalein is an inhibitor of 15-LO and CYP2C9.

用途

An inhibitor of Ca2+ uptake, 5-LO, and 12-LO

生化机理

中药类黄酮的组成成分，黄芩的主要黄酮，抑制花生四烯酸代谢中的12-脂肪氧化酶路径（12-lipoxygenase ，12-LOX），此路径能抑制癌细胞的增殖，诱导凋亡途径。

标识符号	GHS07
信号词	Warning
危害声明	H315,H319,H335
警示性声明	P261,P305+P351+P338
个人防护设备	dust mask type N95 (US),Eyeshields,Gloves
危害码（欧洲）	Xi
风险声明 (欧洲)	R36/37/38;
安全声明（欧洲）	S26;S36;
RIDADR	否
WGK德国	3
闪点（华氏）	N/A
Merck Index	942
是否危化品	否

{uname}

{comment_time|今天}

{content|默认评论}

{uname}

{comment_time|今天}

{content|默认好评}

{uname}

{comment_time|今天}

{content|默认中评}

{uname}

{comment_time|今天}

{content|默认差评}

属性

描述

共有(72)人参考评价