• 白藜芦醇,99%
  • W42006 501-36-0

    Resveratrol

产品订购
产品货号重量货期 优惠价 数量
W42006-1g 1g 准现货 询价
W42006-25g 25g 准现货 询价
W42006-5g 5g 准现货 询价
  • 产品信息

属性

存贮条件 储存温度-20°C
密度 1.3590
荧光
IC50
pK Values

描述

别名 芪三酚;3,4‘,5-三羟基芪;反式-1,2-(3,4‘,5-三羟基二苯基)乙烯;(E)-5-[2-(4-羟苯基)-乙烯基]-1,3-苯二酚;3,4‘,5-Trihydroxy-trans-stilbene;trans-1,2-(3,4‘,5-Trihydroxydiphenyl)ethylene
产品介绍 无味、完全溶解于乙醇。
用途 COX−1选择性抑制剂。白藜芦醇是一种酚类植物抗毒素,发现于葡萄皮和其他植物中。它具有细胞内抗氧化活性激活去乙酰化酶SIRT1。白藜芦醇的抗糖尿病、神经保护和抗脂特性都可能是去乙酰化酶SIRT1激活所致。
生化机理

Resveratrol is a phenolic phytoalexin found in grape skin and other plants. Resveratrol produced neurotrophic effects on cultured DA neurons. Resveratrol could attenuate oxidant-induced mitochondrial damage in embryonic rat cardiomyocytes by inactivating GSK-3β via cGMP/PKG signaling pathway independent of NO-related mechanism. Because Resveratrol has anti-inflammatory, anti-oxidant, and hypotriglyceridemic effects, its supplementation may beneficially affect the increased cardiovascular risk of healthy smokers. Resveratrol merits investigation as a potential cancer chemopreventive agent in humans. trans-Resveratrol is a potent phenolic antioxidant found in grapes and red wine that also has antiproliferative and anti-inflammatory activity. trans-Resveratrol is also a selective inhibitor of cyclooxygenase-1 (COX-1). It inhibits COX and peroxidase activities of COX-1 with ED50 values of 15 and 3.7 ?M, respectively; with essentially no inhibition of the COX activity

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