G68761 32981-86-5
10-Deacetylbaccatin III
存贮条件 | 贮存温度2-8℃ |
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熔点 | 231-236°C |
密度 | 1.4100 |
荧光 | 否 |
IC50 | 否 |
pK Values | 否 |
别名 | 10-脱乙酰基巴卡丁 III ;10-去乙酰基巴卡亭;10-DAB |
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产品介绍 | 不溶于水,溶于甲醇、丙酮和吡啶。 |
用途 | 紫杉醇及其衍生物的合成中间体。 |
生化机理 |
10-Deacetylbaccatin-III is an intermediate for taxol analog preparations. Taxols have exhibit antitumor agents. Several of these taxols can be synthesized from 10- Deacetylbaccatin-III. 10-Deacetylbaccine III is the fifth intermediate of paclitaxel biosynthesis. The biosynthetic pathway consists of approximately 20 enzymatic steps but is not fully elucidated. 10-Deacetylbaccine III is an antineoplastic agent and an anti-cancer intermediate. |
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