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  • 酒石酸长春瑞滨 ,HPLC≥98%

  • G68771 125317-39-7

    Vinorelbine Ditartrate salt hydrate

产品订购
产品货号规格货期 优惠价 数量
G68771-20mg 20mg 准现货 询价
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  • 产品信息

属性

存贮条件 储存温度2-8℃
熔点 181°C-183°C
密度 否
荧光 否
IC50 否
pK Values 否

描述

别名 长春瑞宾双酒石酸盐;3‘,4‘-Didehydro-4‘-deoxy-C‘-norvincaleukoblastine [R-?(R*,R*)?-?2-?3-?dihydroxybutanedioate (1:2)salt], 5‘-Noranhydrovinoblastine tartrate, KW-2307, NVB, Navelbine tartrate
产品介绍 Vinorelbine ditartrate is a selective mitotic microtubule antagonist that exhibits > 20 fold selectivity over axonal microtubules. This compound has been shown to inhibit the proliferation of multiple human tumor cell lines (IC50 = 1.25 nM in HeLa cells).
生化机理 Vinorelbine is a potent anti-mitotic, anti-tumor agent. Vinorelbine inhibits microtubule assembly. Low neurotoxicity is related to its higher affinity for mitotic microtubules than for axonal microtubules.

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