• 卡托普利 ,≥98%
  • G63607 62571-86-2

    Captopril

产品订购
产品货号重量货期 优惠价 数量
G63607-5g 5g 准现货 询价
G63607-25g 25g 准现货 询价
G63607-100g 100g 准现货 询价
G63607-500g 500g 准现货 询价
  • 产品信息

属性

溶解性 Soluble in water (160 mg/ml) at 25 °C, sesame and corn oils (<1 mg/ml) at 25 °C, methanol (>100 mg/ml), ethanol (>100 mg/ml), isopropanol (>100 mg/ml), chloroform (>100 mg/ml), and dichloromethane (>100 mg/ml).
敏感性 对空气敏感
存贮条件 储存温度-20°C
熔点 106°C
密度
旋光率 -127.5°
荧光
IC50
pK Values

描述

别名 N-[(S)-3-巯基-2-甲基丙酰基]-L-脯氨酸;(S)-1-(3-巯基-2-甲基-1-氧代丙基)-L-脯氨酸;巯甲丙脯酸;1-((2S)-2-甲基-3-巯基-1-氧代丙基)-L-脯氨酸;Capoten; Cesplon; L-Captopril;N-[(S)-3-Mercapto-2-methylpropionyl]-L-proline;(S)-(-)-1-(3-Mercapto-2-methyl-1-oxopropyl)-L-proline ;(S)-(-)-1-(3-Mercapto-2-methylpropionyl)-L-proline
产品介绍 Captopril is a reversible and competitive inhibitor of leukotriene A4 hydrolase (LTA4H; IC50 = 11μM). Captopril has been shown to be an inhibitor of angiotensin converting enzyme-1 (ACE1), but not ACE2 (IC50 = 22 nM). Captopril demonstrates noncompetitive inhibition of tyrosinase monophenolase activity and competitive inhibition of diphenolase activity. Captopril has also been shown to inhibit the formation of angiotensin II, a bioactive peptide that stimulates angiogenesis and increases microvessel density.
用途 Captopril是一种血管紧张素转换酶(ACE)抑制剂,IC50为6 nM。
生化机理 血管紧张素转换酶抑制剂。抑制血管紧张素 II 的形成,血管紧张素 II 是生物活性多肽,可促进血管生成并增加微血管密度。
备注 Captopril is an angiotensin-converting enzyme (ACE) inhibitor with IC50 of 6 nM.

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