• 天然辣椒碱 , 分析标准品,HPLC≥98%
  • G61533 404-86-4

    Capsaicin

产品订购
产品货号规格货期 优惠价 数量
G61533-20mg 20mg 准现货 询价
  • 产品信息

属性

溶解性 Soluble in ethanol (≥30 mg/mL), ether, chloroform, benzene, DMSO (≥30 mg/mL), DMF (≥30 mg/mL), and PBS (pH 7.2) (≥0.1 mg/mL). Insoluble in water.
存贮条件 储存温度 2-8°C
熔点 65°C
密度 1.0410
荧光
IC50
pK Values

描述

别名 8-甲基-N-[(4-羟基-3-甲氧基苯基)-甲基]-(反)-6-壬烯基酰胺;8-甲基-N-香草基-L-壬烯胺;(E)-N-(4-羟基-3-甲氧基苄基)-8-甲基-6-壬烯酰胺;辣椒素;8-甲基-N-香草基-反-6-壬烯酰胺;8-Methyl-N-vanillyl-6-nonenamide; N-[(4-Hydroxy-3-methoxyphenyl)methyl]-8-methyl-6-nonenamide; (E)-Capsaicin
产品介绍 Capsaicin acts as an agonist at the VR1 (TRPV1) receptor, a ligand-gated non-selective cation channel. It exhibits neuroprotective effects in a model of transient global cerebral ischemia and induces release of substance P from afferent nociceptive specific neurons. Capsaicin also Inhibits NFκB activation by TNF and reversibly inhibits platelet aggregation. Improper activation of NF-κB has been linked to cancer, immune and inflammatory diseases, and viral infection.
用途 A TRPV1 receptor agonist
生化机理 原型辣椒素受体激动剂。神经毒素;激活感觉神经元生成许多包含P物质无髓C纤维,局部应用麻痹感觉神经末梢会给人一种矛盾的抗伤害效果;全身给药对辣椒素敏感的细胞具神经毒性,尤其是在新生动物。辣椒的活性成分。

返回顶部 微信咨询 021-54720761 021-54720761 点我QQ咨询 点我QQ咨询