• 5-氨基水杨酸 ,≥99%
  • G64378 89-57-6

    5-Aminosalicylic acid

产品订购
产品货号重量货期 优惠价 数量
G64378-100g 100g 准现货 询价
G64378-25g 25g 准现货 询价
  • 产品信息

属性

溶解性 Soluble in 1 M hydrochloric acid (50 mg/ml), water (0.84 g/l at 20 °C), alcohol, DMSO (~4 mg/ml), DMF (~1.6 mg/ml), PBS(pH=7.2) (~1.7 mg/ml), methanol, water (1.7 mg/ml at 25 °C), and ethanol (31 mg/ml at 25 °C). Insoluble in diethyl ether, and n-octan
敏感性 对光和空气敏感
存贮条件 储存温度 2-8°C ,充氩储存
熔点 265°C
密度
荧光
IC50
pK Values

描述

别名 5-AS;5-氨基-2-羟基苯甲酸;氨水杨酸;美沙拉秦;5-氨基-2-羟基苯甲酸;3-羧基-4-羟基苯胺;5-Amino-2-hydroxybenzoic acid;5-AS;Mesalamine;Mesalazine;5-Amino-2-hydroxybenzoic Acid
产品介绍 Mesalamine是一种抗炎化合物。
用途 5-氨基水杨酸是一种适用于 ELISA 分析的过氧化物酶底物。该底物生成棕色的可溶性终产物,该产物可通过分光光度法在 450nm 处读取。加入 3N NaOH 可终止反应,然后在 550nm 处进行读取。
生化机理 5-Aminosalicylic Acid, the metabolite of sulphasalazine, has been shown to inhibit PGDH (prostaglandin 15-hydroxydehydrogenase) in human placenta and bovine lung. Further studies show that this antiinflammatory compound also inhibits leukotriene formation in human leukocytes. Additionally, 5-Aminosalicylic acid demonstrates the ability to disrupt TNFα (tumor necrosis factor α)-stimulated NFκB (nuclear factor κB) activation via inhibition of the multimeric IκB kinase regulating complex.
备注 Mesalamine is an anti-inflammatory compound.

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