• 罗丹明123 ,99%
  • G63961 62669-70-9

    Rhodamine 123

产品订购
产品货号重量货期 优惠价 数量
G63961-100mg 100mg 准现货 询价
G63961-5mg 5mg 准现货 询价
G63961-25mg 25mg 准现货 询价
G63961-500mg 500mg 准现货 询价
  • 产品信息

属性

溶解性 Soluble in ethanol (20 mg/ml), DMSO, methanol, and water (partly miscible).
熔点 235°C
密度
荧光
IC50
pK Values

描述

别名 ;2-(6-Amino-3-imino-3H-xanthen-9-yl)benzoic acid methyl ester
产品介绍 Rhodamine 123 is a cationic dye that emits a green fluorescence. Research observations indicate that Rhodamine 123 can be used to probe the electrochemical gradient in mitochondria, in flow cytometry to detect the activity of P-glycoprotein efflux, and as a compound for P-GP mediating transport. Studies report that Rhodamine 123 can decrease the clonal growth of carcinoma cells in vitro, and that it can associate with placental P-gp. Rhodamine 123 is a substrate of Mdr (P-glycoprotein). Rhodamine 123 is a substrate of MRP1.
用途 Useful as a laser dye and to have selective cell growth effects. Mitochondrial specific fluorescent dye and substrate for P-glycoprotein.
生化机理 Fluorescent dye most commonly used in flow cytometry as functional reporter for Pgp. Functional assays for MDR proteins are better prognostic indicators in cancer therapy than levels of MDR protein expression. Rh 123 can be used in multiparameter analyses without fluorescence interference in combination with common protein labeling dyes such as PE-Cy5 and AMCA (7-amino-4-methylcoumarin-3-acetic acid). Recent reports indicate Rh 123 may also be a substrate of MRP1.

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