描述
产品介绍 Guanfacine Hydrochloride是一种选择性的α2A-肾上腺素受体激动剂，具有降压效果。
别名 胍法辛盐酸盐;盐酸胍法辛;N-(氨基亚胺甲基)-2,6-二氯苯乙酰胺盐酸盐;N-甲脒基-2-(2,6-二氯苯基)乙酰胺盐酸盐;N-Amidino-2-(2,6-dichlorophenyl)acetamide Hydrochloride;N-(Aminoiminomethyl)-2,6-dichlorobenzeneacetamide Hydrochloride
生化机理 Guanfacine hydrochloride, a centrally acting anti-hypertensive agent, has been reported to be a specific α2A-AR adrenoceptor agonist. Activation of these α2A-AR adrenoreceptors has been shown to cause a decrease in blood pressure in vitro. Additional studies suggest that Guanfacine hydrochloride plays a role in solute/sodium osmoregulation and excretion.