6-氨基己酸 ,BR，99%使用说明书与操作注意事项

产品货号	重量	货期	优惠价
H03002-100g	100g	准现货	询价
H03002-25g	25g	准现货	询价
H03002-500g	500g	准现货	询价

产品货号

重量

货期

优惠价

数量

H03002-100g

100g

准现货

询价

H03002-25g

25g

准现货

询价

H03002-500g

500g

准现货

询价

溶解性	Soluble in water (50 mg/ml), ethanol (≥1 mg/ml), methanol (sparingly soluble), ether, and DMSO (≥6 mg/ml).
存贮条件	密封干燥保存。
熔点	204-209°C
密度	1.0420
荧光	否
IC50	否
pK Values	否

溶解性

Soluble in water (50 mg/ml), ethanol (≥1 mg/ml), methanol (sparingly soluble), ether, and DMSO (≥6 mg/ml).

存贮条件

密封干燥保存。

熔点

204-209°C

密度

1.0420

荧光

否

IC50

否

pK Values

否

别名	6-氨基己酸 ;氨基己酸,氨己酸,抗血纤溶酸,ε氨基已酸,6-氨基正己酸; EACA;ε-Aminocaproic acid6-Aminohexanoic acidEACAHemocaprol
产品介绍	ε-Amino-n-caproic Acid (EACA) is an antifibrinolytic agent shown to enhance the activation of urinary-type and tissue-type plasminogen, while inhibiting plasminogen activation induced by streptokinase through a kringle-dependent mechanism. Believed to act as a lysine analog that competitively inhibits basic carboxypeptidases, and promotes the rapid dissociation of plasmin by inhibiting activation of plasminogen by streptokinase. Incorporation of EACA into short polypeptide fragments with hydrophobic amino acids yielded cytotoxic compounds against MCF-7 breast cells and fibroblast cells. These factors make EACA a potentially useful compound for research in areas such as: oncology, immunology, and in the general elucidation of biochemical pathways.
用途	EACA is directly soluble in water at 25 mg/ml. As an inhibitor of plasmin it is has been utilized in the clotting buffer for fibrinogen assays. This buffer is 10 mM potassium and sodium phosphate, pH 6.4, with 0.20 g CaCl2, 5 g 6-Aminohexanoic acid, 1 g sodium azide, and 9 g NaCl in 1 liter. The buffer is stable indefinitely at room temperature.
生化机理	EACA is reported to inhibit chymotrypsin, Factor VIIa, lysine carbo-xy-peptidase, plasmin, and plasminogen activator. 赖氨酸类似物。促进纤溶酶快速解离，从而抑制纤溶酶原?的活化以及后续的纤维蛋白溶解。据报告，EACA 可抑制纤溶酶原结合至活化的血小板。早期报告表明，EACA 可抑制补体系统第一组分的活化。结合并灭活羧肽酶 B。

别名

6-氨基己酸 ;氨基己酸,氨己酸,抗血纤溶酸,ε氨基已酸,6-氨基正己酸; EACA;ε-Aminocaproic acid6-Aminohexanoic acidEACAHemocaprol

产品介绍

ε-Amino-n-caproic Acid (EACA) is an antifibrinolytic agent shown to enhance the activation of urinary-type and tissue-type plasminogen, while inhibiting plasminogen activation induced by streptokinase through a kringle-dependent mechanism. Believed to act as a lysine analog that competitively inhibits basic carboxypeptidases, and promotes the rapid dissociation of plasmin by inhibiting activation of plasminogen by streptokinase. Incorporation of EACA into short polypeptide fragments with hydrophobic amino acids yielded cytotoxic compounds against MCF-7 breast cells and fibroblast cells. These factors make EACA a potentially useful compound for research in areas such as: oncology, immunology, and in the general elucidation of biochemical pathways.

用途

EACA is directly soluble in water at 25 mg/ml. As an inhibitor of plasmin it is has been utilized in the clotting buffer for fibrinogen assays. This buffer is 10 mM potassium and sodium phosphate, pH 6.4, with 0.20 g CaCl2, 5 g 6-Aminohexanoic acid, 1 g sodium azide, and 9 g NaCl in 1 liter. The buffer is stable indefinitely at room temperature.

生化机理

EACA is reported to inhibit chymotrypsin, Factor VIIa, lysine carbo-xy-peptidase, plasmin, and plasminogen activator. 赖氨酸类似物。促进纤溶酶快速解离，从而抑制纤溶酶原?的活化以及后续的纤维蛋白溶解。据报告，EACA 可抑制纤溶酶原结合至活化的血小板。早期报告表明，EACA 可抑制补体系统第一组分的活化。结合并灭活羧肽酶 B。

标识符号	GHS07
信号词	Warning
危害声明	H315,H319,H335
警示性声明	P261,P305+P351+P338
个人防护设备	dust mask type N95 (US), Eyeshields, Gloves
危害码（欧洲）	Xi
风险声明 (欧洲)	R36/37/38
安全声明（欧洲）	S26;S37/39
RIDADR	否
WGK德国	2
闪点（华氏）	N/A
是否危化品	否

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