存贮条件 | -20℃保存 |
---|---|
熔点 | 159-161°C |
密度 | 否 |
旋光率 | 15 ° (C=3, MeOH) |
荧光 | 否 |
IC50 | 否 |
pK Values | 否 |
别名 | L-NAME hydrochlorideH-Arg(NO2)-OMe·HCl |
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产品介绍 | 溶于甲醇。 |
用途 | 一种抑制NO生产的精氨酸类似物。在对血管系统多重的效果。抑制乙酰胆碱诱发的舒张,诱导增加动脉血液压力。 |
生化机理 | An analog of arginine that inhibits NO production. It has multiple effects on the vascular system. Inhibits relaxation induced by acetylcholine and induces an increase in arterial blood pressure. Abolishes lecithinized superoxide dismutase induced vasodilation when used to pretreat aortic ring preparations of mice. Induces leukocyte adhesion and increases microvascular fluid and protein fluxes and permeability. It has also been used in many studies of learning and memory. |
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