• Clarithromycin ,≥98%
  • G63593 81103-11-9

    Clarithromycin

产品订购
产品货号重量货期 优惠价 数量
G63593-1g 1g 准现货 询价
G63593-5g 5g 准现货 询价
G63593-25g 25g 准现货 询价
  • 产品信息

属性

溶解性 Soluble in ethanol (<1 mg/ml), water (<1 mg/ml), acetone (50 mg/ml), DMSO (18 mg/ml), and methanol.
存贮条件 储存温度 2-8°C
熔点 225°C
密度
旋光率 -92°C
荧光
IC50
pK Values

描述

别名 克拉仙;克拉霉素;甲氧基红霉素;Biaxin; Biaxin XL; Clarosip; Klaricid; Cyllind;6-O-Methylerythromycin; A-56268; TE-03
产品介绍 Clarithromycin 是一种大环内酯类抗生素,是CYP3A4抑制剂。
用途 A macrolide antibiotic and protein synthesis inhibitor
生化机理 Clarithromycin is a 14-member ring macrolide antibiotic and 6-O-methyl derivative of erythromycin. Clarithromycin has reported bacteriostatic action against gram-positive bacteria and some gram-negative bacteria including anaerobes. Similar to other macrolide antibiotics, this antibiotic is believed to function via binding of the ribosome within the microorganism. Studies have noted that Clarithromycin appears to bind specifically to the 50S ribosomal subunit, thus inhibiting DNA translation and inhibiting bacterial growth. This compound is both a substrate and inhibitor of CYP3A4.
备注 Clarithromycin (Biaxin, Klacid) is a macrolide antibiotic and a CYP3A4 inhibitor.

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