别名
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5-溴-2‘-脱氧尿苷;5‘-溴尿嘧啶核苷;溴脲苷;5-溴-1-(2-脱氧-β-D-呋喃核糖)尿嘧啶;5-溴脱氧尿苷;5-溴去氧脲苷;5-BrdU;5-BrdU;5-Bromo-1-(2-deoxy-β-D-ribofuranosyl)uracil;5-Bromouracil deoxyriboside;BUdR;2‘-Deoxy-5-bromouridine; BDU; Broxuridine;
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产品介绍
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5-Bromo-2‘-deoxyuridine is a thymidine analog. Useful for the study of DNA synthesis where it is incorporated into DNA in place of thymidine. 5-Bromo-2‘-deoxyuridine can be used to label DNA. The resulting DNA can be used in conjunction with BrdU Monoclonal Antibody for the immunohistochemical analysis of cell proliferation.
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用途
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胸腺嘧啶类似物,在遗传学研究中用作诱变剂(mutagen),在细胞分裂的S-期选择性地插进DNA。
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生化机理
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5-Bromo-2‘-deoxyuridine (5-BrdU) is a thymidine analogue which is incorporated into DNA. 5-BrdU is routinely and extensively used to measure DNA synthesis and to label dividing cells. Consequently 5-BrdU is used to study cell signaling and other processes that induce cell proliferation.
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