• 四环素 ≥98%
  • G63513 60-54-8

    tetracycline

产品订购
产品货号重量货期 优惠价 数量
G63513-25g 25g 准现货 询价
G63513-100g 100g 准现货 询价
G63513-500g 500g 准现货 询价
  • 产品信息

属性

溶解性 Soluble in water (1.7 mg/ml), and methanol (> 20 mg/ml).
敏感性 易吸潮,对光线敏感
存贮条件 储存温度-20°C,充氩保存
密度
荧光
IC50
pK Values

描述

别名 四环素碱;Deschlorobiomycin; Ambramycin; Liquamycin;(2Z,4S,4aS,6S,12aS)-2-(Amino-hydroxymethylidene)-4-dimethylamino-6,10,11,12a-tetrahydroxy-6-methyl-4,4a,5,5a-tetrahydrotetracene-1,3,12-trione
产品介绍 Tetracycline is used for treatment of chronic inflammatory cells. Tetracycline derivatives induce apoptosis in osteoclasts, Jurkat T lymphocyte cells and in cultured monocytes and macrophages.
用途 Tetracycline is a broad spectrum polyketide antibiotic. It is used clinically to treat bacterial infections such as Rocky Mountain spotted fever, typhus fever, tick fevers, Q fever, and Brill-Zinsser disease. It is used to treat upper respiratory infections and acne. It is used to study multidrug resistance as well as potential side effects such as acute pancreatitis.
生化机理 Tetracycline inhibits bacterial protein synthesis elongation at the level of aminoacyl-tRNA binding to the 30S ribosome. Tetracycline passively diffuses through porin channels in the bacterial cell membrane. It also binds to the bacterial 50S ribosomal subunit which may alter the cytoplasmic membrane, causing intracellular components to leak from bacterial cells. Mode of resistance is via loss of cell wall permeability.

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