• 嘌呤霉素盐酸盐 ,≥98%
  • G63517 58-58-2

    Puromycin dihydrochloride

产品订购
产品货号重量货期 优惠价 数量
G63517-25mg 25mg 准现货 询价
G63517-100mg 100mg 准现货 询价
G63517-500mg 500mg 准现货 询价
  • 产品信息

属性

溶解性 Soluble in water (50 mg/ml), ethanol (~1 mg/ml), DMSO (~13 mg/ml), DMF (~14 mg/ml), and PBS, pH 7.2 (~10 mg/ml).
敏感性 对热敏感
存贮条件 储存温度-20°C
密度
荧光
IC50
pK Values

描述

别名 嘌呤霉素二盐酸盐 ;二氢氯化嘌呤毒素;3‘-[α-Amino-p-methoxyhydrocinnamamido]-3‘-deoxy-N,N-dimethyladenosine dihydrochloride ;Stylomycin hydrochloride
产品介绍 Puromycin 2HCl 是一种氨基核苷抗菌素,其可作为蛋白质合成的抑制剂。
用途 An aminonuclease antibiotic used for selection and maintenance of cell lines expressing a transfected pac gene.
生化机理 Puromycin is an aminonuclease antibiotic used for selection and maintenance of cell lines expressing a transfected pac gene, whose product, puromycin-N-acetyl-transferase, inactivates puromycin via acetylation. This product has been cell culture tested and is recommended for selection of stably transfected cells following transfection with Santa Cruz Biotechnology shRNA or Lentiviral particles. BACKGROUND: Puromycin is an antibiotic substance produced by the soil actinomycete Streptomyces alboniger which induces apoptosis in cells by interfering with RNA function, leading to inhibition of protein synthesis. Toxic to both eukaryotic and prokaryotic cells. Believed to act as an acyl-tRNA analogue causing premature chain termination, it has been shown to arrest cells in G2/M phase.

返回顶部 微信咨询 021-54720761 021-54720761 点我QQ咨询 点我QQ咨询