描述
产品介绍 Cephalothin sodium salt is a first generation cephem antibiotic with a wide range antibacterial activity. The compound is active against gram-positive and gram-negative bacteria, and has been tested in respiratory disease and neuromuscular junction studies.
别名 头孢噻吩钠;(6R,7R)-3-乙酰氧甲基-8-氧代-7-[2-(噻吩-2-基)乙酰氨基]-5-硫杂-1-氮杂双环[4.2.0.]辛-2-烯-2-甲酸钠;7-(2-Thienylacetamido)cephalosporanic acid sodium salt; Cephalotin sodium salt; Cefalotin sodium; Sodium cephalothin; Synclotin;
生化机理 Mode of Action: Inhibits cell wall synthesis.Antimicrobial spectrum: Gram-positive cocci.Mode of Resistance: Cephalosporinase production.
应用 Cephalothin is a first-generation cephalosporin antibiotic used to study the mechanism of liposome encapsulated antibiotics,strategies for co-opting β-lactamases of Gram-negative bacteria for treatment of antibiotics,and for immunology studies in relation to antibiotics.It is used to study the effect of expression, binding and inhibition of penicillin-binding proteins especially PBP6 on bacterial cell wall mucopeptide synthesis.