胶原酶,BR,Ⅰ型,>125CDU/mg,ELISA试剂盒-酶联免疫试剂盒-优质生化试剂供应商|上海晶抗生物

产品货号	重量	货期	优惠价	数量
G63242-100MG	100MG	准现货	询价
G63242-500MG	500MG	准现货	询价

产品货号

重量

货期

优惠价

数量

G63242-100MG

100MG

准现货

询价

G63242-500MG

500MG

准现货

询价

存贮条件	储存温度 2-8°C
密度	否
荧光	否
IC50	否
pK Values	否

存贮条件

储存温度 2-8°C

密度

否

荧光

否

IC50

否

pK Values

否

别名	梭菌肽酶 A;Clostridiopeptidase A
产品介绍	Crude collagenase preparations contain several isoforms of two different collagenases, a sulfhydryl protease, clostripain, a trypsin-like enzyme, and an aminopeptidase. This combination of collagenolytic and proteolytic activities is effective at breaking down intercellular matrices, the essential part of tissue dissociation. One component of the complex is a hydrolytic enzyme which degrades the helical regions in native collagen preferentially at the Y-Gly bond in the sequence Pro-Y-Gly-Pro, where Y is most frequently a neutral amino acid. This cleavage yields products susceptible to further peptidase digestion. Crude collagenase is inhibited by metal chelating agents such as cysteine, EDTA or o-phenanthroline but not DFP. It is also inhibited by α2-macroglobulin, a large plasma glycoprotein. Ca2+ is required for enzyme activity. Particular enzymatic profiles of each collagenase have been correlated with the tissues from which the cells for study were obtained (or with the uses to which the cells are put) and as a result of the correlations several types of crude collagenases have been established by Aladdin: Types 1, 2, 3, and 4.
用途	This collagenase has been tested with cell lines to verify the product is not cytotoxic. Collagenase is typically used to digest the connective components in tissue samples to liberate individual cells. The concentration for cartilage dispersal is 1-2 mg/ml, but literature searches should be performed for species specific and/or tissue specific concentrations.

别名

梭菌肽酶 A;Clostridiopeptidase A

产品介绍

Crude collagenase preparations contain several isoforms of two different collagenases, a sulfhydryl protease, clostripain, a trypsin-like enzyme, and an aminopeptidase. This combination of collagenolytic and proteolytic activities is effective at breaking down intercellular matrices, the essential part of tissue dissociation. One component of the complex is a hydrolytic enzyme which degrades the helical regions in native collagen preferentially at the Y-Gly bond in the sequence Pro-Y-Gly-Pro, where Y is most frequently a neutral amino acid. This cleavage yields products susceptible to further peptidase digestion. Crude collagenase is inhibited by metal chelating agents such as cysteine, EDTA or o-phenanthroline but not DFP. It is also inhibited by α2-macroglobulin, a large plasma glycoprotein. Ca2+ is required for enzyme activity. Particular enzymatic profiles of each collagenase have been correlated with the tissues from which the cells for study were obtained (or with the uses to which the cells are put) and as a result of the correlations several types of crude collagenases have been established by Aladdin: Types 1, 2, 3, and 4.

用途

This collagenase has been tested with cell lines to verify the product is not cytotoxic. Collagenase is typically used to digest the connective components in tissue samples to liberate individual cells. The concentration for cartilage dispersal is 1-2 mg/ml, but literature searches should be performed for species specific and/or tissue specific concentrations.

标识符号	GHS07, GHS08
信号词	Danger
危害声明	H315,H319,H334,H335
警示性声明	P261,P305+P351+P338,P342+P311
个人防护设备	dust mask type N95 (US), Eyeshields, Faceshields, Gloves
危害码（欧洲）	Xn
风险声明 (欧洲)	R36/37/38;R42
安全声明（欧洲）	S22;S24;S26;S36/37
RIDADR	否
WGK德国	1
闪点（华氏）	N/A

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