• 碳酸酐酶(牛红血球),BR,2500u/mg
  • G63324 9001-03-0

    Carbonic Anhydrase from bovine erythrocytes

产品订购
产品货号重量货期 优惠价 数量
G63324-50mg 50mg 准现货 询价
  • 产品信息

属性

存贮条件 储存温度 2-8°C
密度
荧光
IC50
pK Values

描述

别名 Carbonate Dehydratase;Carbonate Hydrolyase
产品介绍 Carbonic anyhdrase is useful in carboxy group transfers and reduction reactions.
用途 Carbonic anhydrase from bovine erythrocytes (BCA) has been used to study the effect of removal of enzyme-bound metal ion, Zn2+, on aggregation behavior of the enzyme. Removal of metal ion by a chelator such as EDTA enhances the propensity of the enzyme to adopt the molten-globule state. This state of the enzyme is found to bind to the chaperone-like α-crystallin and prevent aggregation. The enzyme from Aladdin has been immobilized to electrochemical transducers in order to obtain develop an analytical device for dissolved CO2 measurement. It has also been used for the thermodynamic analysis of conformational changes in BCA.
生化机理 Carbonic anhydrase is a zinc metalloenzyme that has a molecular weight of approximately 30,000 Da. The enzyme catalyzes the hydration of carbon dioxide to carbonic acid. It is involved in vital physiological and pathological processes such as pH and CO2 homeostasis, transport of bicarbonate and CO2, biosynthetic reactions, bone resorption, calcification, and tumorigenicity. Therefore, this enzyme is an important target for inhibitors with clinical applications for various pathologies such as glaucoma, epilepsy and Parkinson’s disease.

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