梭菌蛋白酶，BR，50u/mg,elisa试剂盒,elisa检测试剂盒,上海晶抗生物工程有限公司

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产品货号	重量	货期	优惠价	数量
G63379-1mg	1mg	准现货	询价
G63379-5mg	5mg	准现货	询价

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别名	;Endoproteinase-Arg-C;Clostridiopeptidase B;Proteinase from Clostridium histolyticum
产品介绍	Clostripain (Endoproteinase-Arg-C) is a two chain proteinase associated with collagenase and isolated from Clostridium histolyticum. It is highly specific for the carboxyl peptide bond of arginine. Clostripain has a sulfhydryl requirement; it is activated by dithiothreitol, cysteine, or other sulfhydryl containing reagents. The presence of calcium ions is essential. The enzyme is inhibited by oxidizing agents and sulfhydryl reactants and by Co2+, Cu2+, Cd2+, and heavy metal ions. Citrate, borate, and Tris anions are less inhibitory.
用途	A protease that cleaves proteins on the carboxyl bond of arginine
生化机理	Clostripain from Clostridium histolyticum is composed of two polypeptide chains, with molecular masses of 41.7 kDa and 15.4 kDa. Clostripain has a highly restricted substrate specificity for Arg-Xaa peptide bonds. Therefore, clostripain has been explored as a potential enzyme for protein sequencing purposes. It has also been studied as a catalyst for condensation of pharmaceutically important peptides containing Arg-Pro bonds.