• 胆固醇氧化酶,BR,10u/mg
  • G63407 9028-76-6

    Cholesterol Oxidase from microorganism

产品订购
产品货号重量货期 优惠价 数量
G63407-200U 200U 准现货 询价
G63407-1ku 1ku 准现货 询价
  • 产品信息

属性

存贮条件 储存温度 -20°C
密度
荧光
IC50
pK Values

描述

别名 ;Oxidase cholesterol;
产品介绍 Cholesterol oxidase has been used in a study to improve treatment of oxysterol-mediated cytotoxicity. Cholesterol oxidase has also been used in a study that determined that cholesterol depletion impairs coupling between channel opening and vesicle release by allowing voltage-gated calcium channels to move further from release sites.Cholesterol oxidase has been used in a study to improve treatment of oxysterol-mediated cytotoxicity. Cholesterol oxidase has also been used in a study that evaluated the effects of cholesterol depletion. This study reported that cholesterol depletion impairs the coupling between channel opening and vesicle release. Additionally, cholesterol oxidase is used to determine serum cholesterol levels. The enzyme also finds application in the microanalysis of steroids in food samples. It has also been used for distinguishing 3-ketosteroids from 3β-hydroxysteroids. Transgenic plants expressing cholesterol oxidase have been investigated in the fight against the cotton boll weevil. CHOD has also been used as a molecular probe to elucidate cellular membrane structures.
用途 Cholesterol oxidase (CHOD) is a monomeric flavoprotein containing FAD that catalyzes the first step in cholesterol catabolism. This bifunctional enzyme oxidizes cholesterol to cholest-5-en-3-one in an FAD-requiring step. The pH optimum of the enzyme is 7.0 to 7.5 and temperature optimum is 50 °C. The pH stability is 5.7-7.8. Hg2+, Ag+, and ionic detergents inhibit the enzyme activity. Molecular mass of the enzyme is 62 kDa. Pathogenic bacteria require CHOD to infect a host‘s macrophage
生化机理 胆固醇氧化酶及胆固醇脂酶一起用于血脂类项目如高密度脂蛋白(HDL-C)、低密度脂蛋白(LDL-C)以及总胆固醇(CHO)等。

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