缬氨霉素 ,≥98% (TLC), ≥95% (HPLC),elisa试剂盒,elisa检测试剂盒,上海晶抗生物工程有限公司

产品货号	重量	货期	优惠价	数量
G63577-10mg	10mg	准现货	询价
G63577-50mg	50mg	准现货	询价

产品货号

重量

货期

优惠价

数量

G63577-10mg

10mg

准现货

询价

G63577-50mg

50mg

准现货

询价

溶解性	Soluble in ethanol (50 mg/ml), DMSO (≥10 mg/ml), petroleum ether, ether, benzene, chloroform, glacial acetic, butyl acetate, and methanol (5 mg/ml). Insoluble in water
敏感性	对光敏感
存贮条件	储存温度-20°C
熔点	190°C
密度	1.0600
荧光	否
IC50	否
pK Values	否

溶解性

Soluble in ethanol (50 mg/ml), DMSO (≥10 mg/ml), petroleum ether, ether, benzene, chloroform, glacial acetic, butyl acetate, and methanol (5 mg/ml). Insoluble in water

敏感性

对光敏感

存贮条件

储存温度-20°C

熔点

190°C

密度

1.0600

荧光

否

IC50

否

pK Values

否

别名	缬氨霉素 ;Cyclo(L-Val-D-HyIva-D-Val-L-Lac-)3: HyIva = α-Hydroxyisovaleric acid, Lac = Lactic acid
产品介绍	Valinomycin is a cyclodepsipeptide and potassium ionophore that has been shown to induce cell death. The compound has been shown to have antibabesial activity and reported to promote hemolysis in HK erythrocytes, and decrease the intracellular ATP concentration. CHO cell studies demonstrate that cells exposed to Valinomycin display caspase-3 activation, phosphatidylserine membrane translocation, and mitochondrial membrane depolarization. Can be used as a biosensor to detect potassium efflux as well.
用途	A potassium ionophore shown to induce cell death;Being a Potassium selective ionophore, valinomycin is used in specific potassium measurment electrodes.Valinomycin is an apoptosis inducer. It is used as a tool in membrane research
生化机理	K+-selective ionophoric cyclodepsipeptide; potassium ionophore which uncouples oxidative phosphorylation, induces apoptosis in murine thymocytes, inhibits NGF-induced neuronal differentiation and antagonizes ET-induced vasoconstriction

别名

缬氨霉素 ;Cyclo(L-Val-D-HyIva-D-Val-L-Lac-)3: HyIva = α-Hydroxyisovaleric acid, Lac = Lactic acid

产品介绍

Valinomycin is a cyclodepsipeptide and potassium ionophore that has been shown to induce cell death. The compound has been shown to have antibabesial activity and reported to promote hemolysis in HK erythrocytes, and decrease the intracellular ATP concentration. CHO cell studies demonstrate that cells exposed to Valinomycin display caspase-3 activation, phosphatidylserine membrane translocation, and mitochondrial membrane depolarization. Can be used as a biosensor to detect potassium efflux as well.

用途

A potassium ionophore shown to induce cell death;Being a Potassium selective ionophore, valinomycin is used in specific potassium measurment electrodes.Valinomycin is an apoptosis inducer. It is used as a tool in membrane research

生化机理

K+-selective ionophoric cyclodepsipeptide; potassium ionophore which uncouples oxidative phosphorylation, induces apoptosis in murine thymocytes, inhibits NGF-induced neuronal differentiation and antagonizes ET-induced vasoconstriction

标识符号	GHS06
信号词	Danger
危害声明	H300,H310
警示性声明	P264,P280,P302+P350,P310
个人防护设备	Eyeshields,Faceshields,full-face particle respirator type N100 (US),Gloves,respirator cartridge type N100 (US),type P1 (EN143) respirator filter,type P3 (EN 143) respirator cartridges
危害码（欧洲）	T+
风险声明 (欧洲)	27/28
安全声明（欧洲）	28,36/37,45
RIDADR	否
WGK德国	3
闪点（华氏）	N/A
RTECS	YV9468000
UN代码	2811
是否危化品	否

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