Glimepiride ,≥99%,ELISA试剂盒-酶联免疫试剂盒-优质生化试剂供应商|上海晶抗生物

产品货号	重量	货期	优惠价	数量
G63583-1g	1g	准现货	询价
G63583-5g	5g	准现货	询价

产品货号

重量

货期

优惠价

数量

G63583-1g

准现货

询价

G63583-5g

准现货

询价

溶解性	Soluble in DMSO (>10 mg/ml), water (<1 mg/ml at 25 °C), and ethanol (<1 mg/ml at 25 °C).
密度	否
荧光	否
IC50	否
pK Values	否

溶解性

Soluble in DMSO (>10 mg/ml), water (<1 mg/ml at 25 °C), and ethanol (<1 mg/ml at 25 °C).

密度

否

荧光

否

IC50

否

pK Values

否

别名	贺普丁;格列美脲;格列吡咯;1-[4-[2-(3-乙基-4-甲基-2-氧代-3-吡咯啉-1-甲酰胺基)-乙基]-苯磺酰]-3-(反式-4-甲基环己基)-脲;反式-3-乙基-2,5-二氢-4-甲基-N-[2-[4-[[[[(4-甲基环己基)氨基]羰基]氨基]磺酰基]苯基]乙基]-2-氧-1H-吡咯-1-羧酰胺;
产品介绍	Glimepiride is a third generation sulfonylurea compound, which increases the release of insulin from pancreatic beta cells. In addition, Glimepiride increases the activity of intracellular insulin receptors. Studies conducted on adipocytes and skeletal muscle suggest that Glimepiride induces the PI3 kinase (PI3K) and Akt pathway, along with insulin receptor substrate-1/2 and endothelial nitric oxide synthase. Glimepiride also increases osteoblast proliferation and differentiation, which is thought to be related to its ability to activate the PI3K and Akt pathway. Furthermore, Glimepiride enhances intrinsic peroxisome proliferator-activated receptor γ activity. Glimepiride also increases protein expression of glucose transports 1 and 4, and is a potent KIR channel blocker.
用途	A third generation sulfonylurea compound that induces the PI3K and Akt pathway

别名

贺普丁;格列美脲;格列吡咯;1-[4-[2-(3-乙基-4-甲基-2-氧代-3-吡咯啉-1-甲酰胺基)-乙基]-苯磺酰]-3-(反式-4-甲基环己基)-脲;反式-3-乙基-2,5-二氢-4-甲基-N-[2-[4-[[[[(4-甲基环己基)氨基]羰基]氨基]磺酰基]苯基]乙基]-2-氧-1H-吡咯-1-羧酰胺;

产品介绍

Glimepiride is a third generation sulfonylurea compound, which increases the release of insulin from pancreatic beta cells. In addition, Glimepiride increases the activity of intracellular insulin receptors. Studies conducted on adipocytes and skeletal muscle suggest that Glimepiride induces the PI3 kinase (PI3K) and Akt pathway, along with insulin receptor substrate-1/2 and endothelial nitric oxide synthase. Glimepiride also increases osteoblast proliferation and differentiation, which is thought to be related to its ability to activate the PI3K and Akt pathway. Furthermore, Glimepiride enhances intrinsic peroxisome proliferator-activated receptor γ activity. Glimepiride also increases protein expression of glucose transports 1 and 4, and is a potent KIR channel blocker.

用途

A third generation sulfonylurea compound that induces the PI3K and Akt pathway

RIDADR	否
闪点（华氏）	N/A
是否危化品	否

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描述

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