马来酸氯苯那敏 ,99%,elisa试剂盒,elisa检测试剂盒,上海晶抗生物工程有限公司

产品货号	重量	货期	优惠价
G63584-5g	5g	准现货	询价
G63584-25g	25g	准现货	询价
G63584-100g	100g	准现货	询价

产品货号

重量

货期

优惠价

数量

G63584-5g

准现货

询价

G63584-25g

25g

准现货

询价

G63584-100g

100g

准现货

询价

溶解性	Solubility: Soluble in water
敏感性	对光敏感
熔点	130-135°
密度	否
荧光	否
IC50	否
pK Values	否

溶解性

Solubility: Soluble in water

敏感性

对光敏感

熔点

130-135°

密度

否

荧光

否

IC50

否

pK Values

否

别名	马来酸氯苯那敏;扑尔敏;氯屈米通;马来那敏;Chlorphenamine maleate; Piriton;Puermin; Chlortrimeton
产品介绍	Chlorpheniramine Maleate是一种组胺H1受体拮抗剂，IC50为12 nM。
用途	An antagonist of the histamine H1-receptor.
生化机理	Chlorpheniramine Maleate is a small molecule H1-receptor antagonist. Increased ornithine decarboxylase activity induced in an ischemia-reperfusion state was attenuated by Chlorpheniramine Maleate, indicating that this increase is mediated through engagement of the H1-receptor by histamine. Histamine-mediated repair of intestinal mucosa following ischemia-reperfusion was also demonstrated to operate through the H1-receptor with Chlorpheniramine Maleate. Induction of ornithine decarboxylase was blocked by Chlorpheniramine Maleate in Ehrlich carcinoma and MCF-7 cells. The positive inotropic effect of H1-receptor stimulation by histamine on protein tyrosine phosphorylation in guinea pig left atrium was antagonized by Chlorpheniramine Maleate.
备注	Chlorpheniramine (Chlorpheniramine maleate, Chlorphenamine) is an histamine H1 receptor antagonist with IC50 of 12 nM.

别名

马来酸氯苯那敏;扑尔敏;氯屈米通;马来那敏;Chlorphenamine maleate; Piriton;Puermin; Chlortrimeton

产品介绍

Chlorpheniramine Maleate是一种组胺H1受体拮抗剂，IC50为12 nM。

用途

An antagonist of the histamine H1-receptor.

生化机理

Chlorpheniramine Maleate is a small molecule H1-receptor antagonist. Increased ornithine decarboxylase activity induced in an ischemia-reperfusion state was attenuated by Chlorpheniramine Maleate, indicating that this increase is mediated through engagement of the H1-receptor by histamine. Histamine-mediated repair of intestinal mucosa following ischemia-reperfusion was also demonstrated to operate through the H1-receptor with Chlorpheniramine Maleate. Induction of ornithine decarboxylase was blocked by Chlorpheniramine Maleate in Ehrlich carcinoma and MCF-7 cells. The positive inotropic effect of H1-receptor stimulation by histamine on protein tyrosine phosphorylation in guinea pig left atrium was antagonized by Chlorpheniramine Maleate.

备注

Chlorpheniramine (Chlorpheniramine maleate, Chlorphenamine) is an histamine H1 receptor antagonist with IC50 of 12 nM.

标识符号	GHS06
信号词	Danger
危害声明	H301
警示性声明	P301 + P310
个人防护设备	Eyeshields, Faceshields, Gloves, type P2 (EN 143) respirator cartridges
RIDADR	否
WGK德国	3
闪点（华氏）	N/A
RTECS	US6504000
是否危化品	否

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