甲氨蝶呤 ACS级，98%,elisa试剂盒,elisa检测试剂盒,上海晶抗生物工程有限公司

产品货号	重量	货期	优惠价
G63626-1g	1g	准现货	询价
G63626-5g	5g	准现货	询价
G63626-25g	25g	准现货	询价

产品货号

重量

货期

优惠价

数量

G63626-1g

准现货

询价

G63626-5g

准现货

询价

G63626-25g

25g

准现货

询价

溶解性	易溶于稀碱、酸或碱金属的碳酸盐溶液,微溶于稀盐酸,几乎不溶于水、乙醇、氯仿、乙醚.
敏感性	对光和湿度敏感
存贮条件	储存温度 -20°C
密度	1.5360
旋光率	21 ° (C=0.1, 1N NaOH)
荧光	否
IC50	否
pK Values	否

溶解性

易溶于稀碱、酸或碱金属的碳酸盐溶液,微溶于稀盐酸,几乎不溶于水、乙醇、氯仿、乙醚.

敏感性

对光和湿度敏感

存贮条件

储存温度 -20°C

密度

1.5360

旋光率

21 ° (C=0.1, 1N NaOH)

荧光

否

IC50

否

pK Values

否

别名	胺甲喋呤水合物;L-氨甲喋呤水合物;MTX 水合物;氟安定水合物;氨甲叶酸水合物;氨甲喋呤水合物;对-[(2,4-二氨基喋啶-6)-N-甲基甲氨基]苯甲酰谷氨酸水合物;N-[4-[[(2,4-二氨基-6-蝶啶)甲基]甲氨基]苯甲酰]-L-谷氨酸水合物;(+)-Amethopterin Hydrate;MTX hydrate;Antifolan hydrate;Methylaminopterin hydrate;L-Amethopterin hydrate;4-Amino-10-methylfolic acid hydrate;L-4-Amino-N¹⁰-methylpteroylglutamic acid hydrate;
用途	叶酸拮抗剂，二羟基叶酸还原酶（dihydrofolate reductase）抑制剂。
生化机理	Methotrexate trihydrate is the hydrated form of Methotrexate. Methotrexate is a cell cycle arresting agent with varying effects. Methotrexate has been reported to arrest the cell cycle in late G1/S thus leading to the inhibition of the synthesis of DNA, RNA, thymidylates, and proteins. The main mechanism of action is reported to involve the inhibition of enzymes involved in purine metabolism which leads to the accumulation of adenosine or the suppression of intercellular adhesion molecule expression by T cells. Additionally, this compound has been observed to inhibit DHFR. Methotrexate has also been shown to modulate inflammation by promoting adenosine release or inhibiting transmethylation reactions. Methotrexate was also noted to decrease IL-1 production in adherent splenic cells. Additionally offered as, Methotrexate

别名

胺甲喋呤水合物;L-氨甲喋呤水合物;MTX 水合物;氟安定水合物;氨甲叶酸水合物;氨甲喋呤水合物;对-[(2,4-二氨基喋啶-6)-N-甲基甲氨基]苯甲酰谷氨酸水合物;N-[4-[[(2,4-二氨基-6-蝶啶)甲基]甲氨基]苯甲酰]-L-谷氨酸水合物;(+)-Amethopterin Hydrate;MTX hydrate;Antifolan hydrate;Methylaminopterin hydrate;L-Amethopterin hydrate;4-Amino-10-methylfolic acid hydrate;L-4-Amino-N¹⁰-methylpteroylglutamic acid hydrate;

用途

叶酸拮抗剂，二羟基叶酸还原酶（dihydrofolate reductase）抑制剂。

生化机理

Methotrexate trihydrate is the hydrated form of Methotrexate. Methotrexate is a cell cycle arresting agent with varying effects. Methotrexate has been reported to arrest the cell cycle in late G1/S thus leading to the inhibition of the synthesis of DNA, RNA, thymidylates, and proteins. The main mechanism of action is reported to involve the inhibition of enzymes involved in purine metabolism which leads to the accumulation of adenosine or the suppression of intercellular adhesion molecule expression by T cells. Additionally, this compound has been observed to inhibit DHFR. Methotrexate has also been shown to modulate inflammation by promoting adenosine release or inhibiting transmethylation reactions. Methotrexate was also noted to decrease IL-1 production in adherent splenic cells. Additionally offered as, Methotrexate

风险声明 (欧洲)	R25;R46;R60;R61;R36/37/38
安全声明（欧洲）	S37/39/;S45;S53
RIDADR	否
闪点（华氏）	N/A
Merck Index	5985
UN代码	1544

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