别名
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硫酸阿米卡星; O-3-氨基-3-脱氧-alpha-D-葡吡喃糖基-(1→6)-O-[(6-氨基-6-脱氧-alpha-D-葡吡喃糖基-(1→4)]-N-(4-氨基-2-羟基-1-氧丁基)-2-脱氧-D-链霉胺硫酸盐;Amikacin disulfate salt; 4-Amino-N-[5-amino-2-[4-amino-3,5-dihydroxy-6-(hydroxymethyl)tetrahydropyran-2-yl]oxy-4-[6-(aminomethyl)-3,4,5-trihydroxy-tetrahydropyran-2-yl]oxy-3-hydroxy-cyclohexyl]-2-hydroxy-butanamide disulfate salt;Amikin sulfate; BAY-416651 sulfate
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产品介绍
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Amikacin sulfate是一种半合成,水溶性的卡那霉素氨基糖苷类衍生物 ,可以结合到细菌30S 核糖体亚基上引起mRNA读取错误从而导致细菌不能合成自身生长所必需的蛋白。
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用途
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An aminoglycoside antibiotic that is active against gram-negative bacteria
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生化机理
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Amikacin disulfate, also known as BB-K 8, is an aminoglycoside antibiotic that is active against gram-negative bacteria. The activity of Amikacin is similar to that of Kanamycin and Gentamicin. Amikacin has been used in different types of renal studies. We supply the Amikacin disulfate form
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备注
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Amikacin sulfate binds to 16S rRNA (bacterial 30S ribosome), causing misreading of mRNA and supressing proteins synthesis.
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