• 迷迭香酸 ,97%
  • G61821 20283-92-5

    Rosmarinic acid

产品订购
产品货号重量货期 优惠价 数量
G61821-1g 1g 准现货 询价
G61821-5g 5g 准现货 询价
  • 产品信息

属性

溶解性 Soluble in water (100 mM), ethanol (~25 mg/ml), DMSO (~25 mg/ml), DMF (~25 mg/ml), and PBS (pH 7.2) (~15 mg/ml).
敏感性 对空气敏感
存贮条件 充氩保存
熔点 171-175°C
密度
荧光
IC50
pK Values

描述

别名 (R)-O-(3,4-二羟基肉桂酰)-3-(3,4-二羟苯基)乳酸;3,4-二羟基肉桂酸;(R)-1-羧基-2-(3,4-二羟苯)乙酯;(R)-O-(3,4-Dihydroxycinnamoyl)-3-(3,4- dihydroxyphenyl)lactic acid;3,4-Dihydroxycinnamic acid (R)-1-carboxy-2-(3,4-dihydroxyphenyl)ethyl ester
用途 An activator of GPR35.
生化机理 Rosmarinic Acid is a phenylpropanoid isolated from Labiatae herbs. The compound exhibits antiinflammatory activity and inhibits the proliferation of murine mesangial cells. Rosmarinic Acid has been shown to dose dependently inhibit migration, adhesion, and invasion of Ls174-T human colon carcinoma cells. Rosmarinic Acid has been documented to increase the melanin content in B16 melanoma cells through activation of protein kinase A. In the same study rosmarinic acid induced the phosphorylation of CRE-binding protein (CREB) and activated cAMP response element (CRE). In the classical complement pathway Rosmarinic Acid inhibited C3-convertase. It also has shown to be an activator of GPR35.

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